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Pozdnyakova O., Cand.Sci.(Eng.), Associate Professor of the Department of Agrobiotechnology, Kuzbass State Agricultural Academy,

Kazakova M., Research of the Scientific and Educational Center ‘Processing of agricultural raw materials and food technologies’, Kuzbass State Agricultural Academy,

Avstrievskikh A., Dr.Sci.(Eng.), Professor, General Director of the Scientific Production Association ‘ArtLife’

Poznyakovskiy V., Dr.Sci.(Bio.), Professor, Head of the Department of Food Industry and Functional Nutrition, Head of the Scientific and Educational Center ‘Processing of agricultural raw materials and food technologies’, Kuzbass State Agricultural Academy,

Year 2019 Issue 4 UDC 577.16:664
DOI 10.21603/2074-9414-2019-4-652-659
Abstract Introduction. Hypovitaminosis is currently common among various social groups. The present research offers a new medical formulation that includes a complex of antioxidant vitamins with a highly beneficial synergistic effect.
Study objects and methods. The research employed the SF-36 questionnaire to assess the quality of life in patients with chronic diseases, as recommended by the WHO. The SF-36 questionnaire provides a quantitative description of the physical, emotional, and social components of the quality of life. Clinical control was performed on days 31–32 from the onset of the medication. The state of the microcirculatory bed was assessed in laboratory conditions by applying pressure to the nail bed. The concentration of malondialdehyde was determined by the method developed by M. Uchiyama and M. Mihara.
Results and discussion. The paper introduces the formulation and describes the properties of each component. The efficacy of the medicine was confirmed experimentally. Twenty education and health workers were administered the medicine for one month. The control group consisted of fifteen volunteers, who were randomized and grouped according to professional factor, sex, and age. The control group consumed the medicine together with standard vitamins A, C, and E in adequate dosages.
Conclusion. The developed medicine proved able to improve the physical, social, and emotional aspects of life quality under high psychophysical stress. The polyvalent effect of the components demonstrated a tropism to collagen synthesis. In addition, it showed an antioxidant effect and improved microcirculation. The medicine can be used preventively to reduce the risk of chronic pathology based on the accumulation of excess free radical activity.
Keywords Nutrition, vitamin deficiency, antioxidants, diseases, quality of life, stress
Artice information Received July 30, 2019
Accepted October 15, 2019
Available online December 9, 2019
For citation Pozdnyakova OG, Kazakova MA, Austrievskih AN, Poznyakovsky VM. Effect of Antioxidant Vitamin Complex on Disease Prevention. Food Processing: Techniques and Technology. 2019;49(4):652–659. (In Russ.)
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