Abstract

Sucrose is an important component in many foods. However, it can be dangerous for consumers’ health, if overconsumed. For instance, it may cause tooth decay. As a rule, sucrose provides sweetness and a certain dry matter content. Alternative sweeteners and bulking agents can also perform these two functions. Unfortunately, they almost always fail to serve as an osmotically active agent in canned products. The research objective was to study the properties of trehalose and isomaltulose as sugar substitutes in sweetened condensed milk.
The study covered fifteen years of domestic and foreign research reported in the open databases of the Russian Scientific Citation Index, Scopus, and Web of Science. The list of search descriptors included twelve words and word combinations, e.g., sweetened condensed milk, water activity, sucrose, trehalose, isomaltulose, etc.
The review focused primarily on the important properties of sucrose in the sweetened condensed milk and the physico-chemical features of the milk system. The analysis provided a system of criteria to evaluate the optimality of alternative substances for sweet concentrated milk production. These criteria were applied to trehalose and isomaltulose.
The article introduces a list of criteria that can be used to evaluate sweeteners and sugar substitutes as regulators of certain technological properties in the production of sweetened concentrated milk products with intermediate moisture content. According to these criteria, trehalose and isomaltulose can serve as alternative sweeteners in condensed milk. However, the review revealed some gaps in experimental data on a number of properties of considered carbohydrates in sweetened concentrated milk products, which imposes further research.

Keywords

Sweetened condensed milk, sucrose, cariogenicity, sweeteners, trehalose, isomaltulose, disaccharides

REFERENCES

1. Federal Service for Supervision of Consumer Protection and Rights and Human Welfare [Internet]. [cited 2022 Mar 14]. Available from: https://www.rospotrebnadzor.ru
2. Leontyev VK. Dental caries as a civilization disease. Biosfera. 2010;2(3):392–396. (In Russ.).
3. Lodi CS, de Oliveira LV, Brighenti FL, Delbem ACB, Martinhon CCR. Effects of probiotic fermented milk on biofilms, oral microbiota, and enamel. Brazilian Oral Research. 2015;29(1). https://doi.org/10.1590/1807-3107BOR-2015.vol29.0033
4. Farias da Cruz M, Baraúna Magno M, Alves Jural L, Pimentel TC, Masterson Tavares Pereira Ferreira D, Almeida Esmerino E, et al. Probiotics and dairy products in dentistry: A bibliometric and critical review of randomized clinical trials. Food Research International. 2022;157. https://doi.org/10.1016/j.foodres.2022.111228
5. Kakleas K, Christodouli F, Karavanaki K. Nonalcoholic fatty liver disease, insulin resistance, and sweeteners: a literature review. Expert Review of Endocrinology and Metabolism. 2020;15(2):83–93. https://doi.org/10.1080/17446651.2020.1740588
6. Clemens RA, Jones JM, Kern M, Lee S-Y, Mayhew EJ, Slavin JL, et al. Functionality of sugars in foods and health. Comprehensive Reviews in Food Science and Food Safety. 2016;15(3):433–470. https://doi.org/10.1111/1541-4337.12194
7. Sawale PD, Shendurse AM, Mohan MS, Patil GR. Isomaltulose (Palatinose) – An emerging carbohydrate. Food Bioscience. 2017;18:46–52. https://doi.org/10.1016/j.fbio.2017.04.003
8. Goldfein KR, Slavin JL. Why sugar is added to food: Food science 101. Comprehensive Reviews in Food Science and Food Safety. 2015;14(5):644–656. https://doi.org/10.1111/1541-4337.12151
9. Galstyan AG, Petrov AN, Radaeva IA, Turovskaya SN, Chervetsov VV, Illarionova EE, et al. Theory and practice of dairy canning. Moscow: Izdatelʹskiy dom “Fedotov D.A.”; 2016. 181 p. (In Russ.).
10. Strizhko MN, Galstyan AG. Analysis and systematization of alternative of sucrose osmotically active substances. Newsletter of North-Caucasus Federal University. 2013;35(2):97–101. (In Russ.).
11. Tapia MS, Alzamora SM, Chirife J. Effects of water activity (aw) on microbial stability as a hurdle in food preservation. In: Barbosa-Cánovas GV, Fontana Jr. AJ, Schmidt SJ, Labuza TP, editors. Water activity in foods: Fundamentals and applications. John Wiley & Sons; 2020. pp. 323–355. https://doi.org/10.1002/9781118765982.CH14
12. Illarionova EE, Radaeva IA, Turovskaya SN, Guseva TB. Water activity in the products with intermediate moisture. Dairy Industry. 2017;(10):15–16. (In Russ.).
13. Galstyan AG. Scientific foundations and practical solutions for improving technologies and expanding the range of canned milk. Abstract dr. eng. sci. diss. Moscow: V.M. Gorbatov All-Russian Research Institute of the Meat Industry; 2009. 50 p. (In Russ.).
14. Gómez-Narváez F, Contreras-Calderón J, Pérez-Martínez L. Usefulness of some Maillard reaction indicators for monitoring the heat damage of whey powder under conditions applicable to spray drying. International Dairy Journal. 2019;99. https://doi.org/10.1016/j.idairyj.2019.104553
15. Arena S, Renzone G, D'Ambrosio C, Salzano AM, Scaloni A. Dairy products and the Maillard reaction: A promising future for extensive food characterization by integrated proteomics studies. Food Chemistry. 2017;219:477–489. https://doi.org/10.1016/j.foodchem.2016.09.165
16. ALjahdali N, Carbonero F. Impact of Maillard reaction products on nutrition and health: Current knowledge and need to understand their fate in the human digestive system. Critical Reviews in Food Science and Nutrition. 2019;59(3):474–487. https://doi.org/10.1080/10408398.2017.1378865
17. Cortés Yáñez DA, Gagneten M, Leiva GE, Malec LS. Antioxidant activity developed at the different stages of Maillard reaction with milk proteins. LWT. 2018;89:344–349. https://doi.org/10.1016/j.lwt.2017.11.002
18. Wu J, Li H, A'yun Q, Sedaghat Doost A, De Meulenaer B, Van der Meeren P. Conjugation of milk proteins and reducing sugars and its potential application in the improvement of the heat stability of (recombined) evaporated milk. Trends in Food Science and Technology. 2021;108:287–296. https://doi.org/10.1016/j.tifs.2021.01.019
19. Petrov AN, Galstyan AG, Radaeva IA, Turovskaya SN, Illarionov EE, Semipyatniy VK, et al. Indicators of quality of canned milk: Russian and international priorities. Foods and Raw Materials. 2017;5(2):151–161. https://doi.org/10.21603/2308-4057-2017-2-151-161
20. Illarionova EE, Turovskaya SN, Radaeva IA. To the question of increasing of canned milk storage life. Relevant Issues of the Dairy Industry, Cross-Industry Technologies, and Quality Management Systems. 2020;1(1):225–230. (In Russ.). https://doi.org/10.37442/978-5-6043854-1-8-2020-1-225-230
21. Rjabova AE, Kirsanov VV, Strizhko MN, Bredikhin AS, Semipyatnyi VK, Chervetsov VV, et al. Lactose crystallization: Current issues and promising engineering solutions. Foods and Raw Materials. 2013;1(1):66–73. https://doi.org/10.12737/1559
22. Radaeva IA, Turovskaya SN, Illarionova EE, Kulikovskaya TS. Structural changes of concentrated milk with sugar in the course of long storage. Dairy Industry. 2017;(9):60–72. (In Russ.).
23. Rjabova AE, Galstjan AG, Malova TI, Radaeva IA, Turovskaja SN. Heterogeneous crystallization of lactose in technology of sweetened condensed milk. Food Processing: Techniques and Technology. 2014;32(1):78–83. (In Russ.).
24. Petrov SM, Arapov DV, Kuritsyn VA. Physical and chemical properties of aqueous sucrose solutions: Equations for digital calculations. Sugar. 2014;(4):44–53. (In Russ.).
25. Mahato DK, Keast R, Liem DG, Russell CG, Cicerale S, Gamlath S. Sugar reduction in dairy food: an overview with flavoured milk as an example. Foods. 2020;9(10). https://doi.org/10.3390/foods9101400
26. Ohtake S, Wang YJ. Trehalose: Current use and future applications. Journal of Pharmaceutical Sciences. 2011;100(6):2020–2053. https://doi.org/10.1002/jps.22458
27. Feofilova EP, Usov AI, Mysyakina IS, Kochkina GA. Trehalose: chemical structure, biological functions, and practical application. Microbiology. 2014;83(3):271–283. (In Russ.). https://doi.org/10.7868/S0026365614020074
28. Cai X, Seitl I, Mu W, Zhang T, Stressler T, Fischer L, et al. Biotechnical production of trehalose through the trehalose synthase pathway: Current status and future prospects. Applied Microbiology and Biotechnology. 2018;102(7):2965–2976. https://doi.org/10.1007/s00253-018-8814-y
29. Leiva GE, Naranjo GB, Malec LS. A study of different indicators of Maillard reaction with whey proteins and different carbohydrates under adverse storage conditions. Food Chemistry. 2017;215:410–416. https://doi.org/10.1016/j.foodchem.2016.08.003
30. Rehan F, Ahemad N, Gupta M. Casein nanomicelle as an emerging biomaterial – A comprehensive review. Colloids and Surfaces B: Biointerfaces. 2019;179:280–292. https://doi.org/10.1016/j.colsurfb.2019.03.051
31. Barbiroli A, Marengo M, Fessas D, Ragg E, Renzetti S, Bonomi F, et al. Stabilization of beta-lactoglobulin by polyols and sugars against temperature-induced denaturation involves diverse and specific structural regions of the protein. Food Chemistry. 2017;234:155–162. https://doi.org/10.1016/J.FOODCHEM.2017.04.132
32. He F, Woods CE, Litowski JR, Roschen LA, Gadgil HS, Razinkov VI, et al. Effect of sugar molecules on the viscosity of high concentration monoclonal antibody solutions. Pharmaceutical Research. 2011;28(7):1552–1560. https://doi.org/10.1007/s11095-011-0388-7
33. Jain NK, Roy I. Effect of trehalose on protein structure. Protein Science. 2009;18(1):24–36. https://doi.org/10.1002/pro.3
34. Amariei S, Norocel L, Scripcă LA. An innovative method for preventing honey crystallization. Innovative Food Science and Emerging Technologies. 2020;66. https://doi.org/10.1016/j.ifset.2020.102481
35. Thorat AA, Forny L, Meunier V, Taylor LS, Mauer LJ. Effects of mono-, di-, and tri-saccharides on the stability and crystallization of amorphous sucrose. Journal of Food Science. 2018;83(11):2827–2839. https://doi.org/10.1111/1750-3841.14357
36. Singh SK. Sucrose and trehalose in therapeutic protein formulations. In: Warne NW, Mahler H-C, editors. Challenges in protein product development. Cham: Springer; 2018. pp. 63–95. https://doi.org/10.1007/978-3-319-90603-4_3
37. Russ N, Zielbauer BI, Vilgis TA. Impact of sucrose and trehalose on different agarose-hydrocolloid systems. Food Hydrocolloids. 2014;41:44–52. https://doi.org/10.1016/j.foodhyd.2014.03.020
38. Palatinose [Internet]. [cited 2022 May 17]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Palatinose
39. Podgornova NM, Petrov SM, Petryanina TA. Isomaltulose, an innovative low-glycemic carbohydrate sweetener. Storage and Processing of Farm Products. 2017;(11):14–20. (In Russ.).
40. Lee EJ, Moon Y, Kweon M. Processing suitability of healthful carbohydrates for potential sucrose replacement to produce muffins with staling retardation. LWT. 2020;131. https://doi.org/10.1016/j.lwt.2020.109565
41. Di Monaco R, Miele NA, Cabisidan EK, Cavella S. Strategies to reduce sugars in food. Current Opinion in Food Science. 2018;19:92–97. https://doi.org/10.1016/j.cofs.2018.03.008
42. Strizhko MN. Prospects for alternative types of osmotically active substances in the dairy industry. Scientific contribution of young scientists to the development of the food and processing industry of the agro-industrial complex: Proceedings of the VII conference of young scientists and specialists from research institutes of the Department of storage and processing of agricultural products of the Russian Agricultural Academy; 2013; Moscow. Moscow: VNIMI; 2013. p. 418–421. (In Russ.).
43. Periche A, Heredia A, Escriche I, Andrés A, Castelló ML. Optical, mechanical and sensory properties of based-isomaltulose gummy confections. Food Bioscience. 2014;7:37–44. https://doi.org/10.1016/j.fbio.2014.05.006
44. Castelló ML, Echevarrías A, Rubio-Arraez S, Ortolá MD. How isomaltulose and oligofructose affect physicochemical and sensory properties of muffins? Journal of Texture Studies. 2021;52(3):410–419. https://doi.org/10.1111/jtxs.12602
45. Peinado I, Rosa E, Heredia A, Andrés A. Use of isomaltulose to formulate healthy spreadable strawberry products. Application of response surface methodology. Food Bioscience. 2015;9:47–59. https://doi.org/10.1016/j.fbio.2014.08.002
46. Song S, Guo J, Qiu J, Liu J, An M, Yi D, et al. Solid-liquid equilibrium of isomaltulose in five pure solvents and four binary solvents from (283.15 to 323.15) K. Journal of Chemical and Engineering Data. 2019;64(3):963–971. https://doi.org/10.1021/acs.jced.8b00823
47. Tan VWK, Wee MSM, Tomic O, Forde CG. Rate-All-That-Apply (RATA) comparison of taste profiles for different sweeteners in black tea, chocolate milk, and natural yogurt. Journal of Food Science. 2020;85(2):486–492. https://doi.org/10.1111/1750-3841.15007
48. Sucrose [Internet]. [cited 2022 May 17]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Sucrose
49. Trehalose [Internet]. [cited 2022 May 17]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Trehalose
50. Bednyh BS, Gapparov MM-G, Nikolskaya GV, Sokolov AI, Ramanauskas IR, Kiselev AYu. Glycolising of proteins in the baby foods. Dairy Industry. 2014;(12):68–69. (In Russ.).
51. Moriano ME, Alamprese C. Honey, trehalose and erythritol as sucrose-alternative sweeteners for artisanal ice cream. A pilot study. LWT. 2017;75:329–334. https://doi.org/10.1016/j.lwt.2016.08.057
52. Borges VC, Salas-Mellado MM. Influence of α-amilase, trehalose, sorbitol, and polysorbate 80 on the quality of gluten-free bread. International Food Research Journal. 2016;23(5):1973–1979.
53. Guggisberg D, Piccinali P, Schreier K. Effects of sugar substitution with Stevia, Actilight™ and Stevia combinations or Palatinose™ on rheological and sensory characteristics of low-fat and whole milk set yoghurt. International Dairy Journal. 2011;21(9):636–644. https://doi.org/10.1016/j.idairyj.2011.03.010
54. Galstyan AG, Radaeva IA, Turovskaya SN, Korchagina SA, Chervetsov VV, Illarionova EE, et al. Brief reference of a specialist in dairy and canning production. Moscow: Ritm; 2011. 152 p. (In Russ.).
55. González-Cruz AS, Sosa-Morales ME, Vélez-Ruiz JF. Effect of sucrose substitution by low-calorie sweeteners on the characteristics of condensed milk. American Society of Agricultural and Biological Engineers Annual International Meeting 2010. Vol. 7. 2010. pp. 5910–5916.