ИССЛЕДОВАНИЕ НЕКОТОРЫХ ОСНОВНЫХ ФАКТОРОВ, ОПРЕДЕЛЯЮЩИХ ПОЛУЧЕНИЕ СУХИХ ПРЕПАРАТОВ ПРОПИОНОВОКИСЛЫХ БАКТЕРИЙ

THE INVESTIGATION ON SOME BASIC FACTORS DETERMINING THE MANUFACTURE OF PROPIONIC ACID BACTERIA OF DRY PREPARATIONS

I.N. Pavlov ^a

Gora ON. ^a

Affiliation

a State Educational Establishmentof Higher Vocational Training Biysk Technological Institute

Copyright ©Pavlov et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0. (http://creativecommons.org/licenses/by/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for any purpose, even commercially, provided the original work is properly cited and states its license.

Abstract

The attention to the problem of manufacturing the dry forms of a propionic preparation based on propionic acid bacteria Propionibacterium freudenreichii has been given. The nutrient medium used for the bifidobacteria growth is reported to be employed as a background medium for culturing bacteria. Some conditions to accumulate bacteria biomass for the nutrient medium have been determined. The following points were considered to be the main factors of the process: temperature maintained, duration, cobalt ion content used as a precursor for B vitamin synthesis. The resulting liquid ferment with a maximum accumulation of propionic bacteria biomass was dried by a spray drying method. While performing the process the manufacture modes were developed that could lead to the minimum bacteria destruction and the survival of a sufficient quantity of live bacteria relative to a liquid ferment.

Keywords

Propionic acid bacteria, nutrient medium, B vitamin, dry ferment, spray drying

REFERENCES

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Воробьева, Л.И. Пропионовокислые бактерии/ Л.И. Воробьева. - М.: Изд-во МГУ, 1995. - 288с.
Нетрусов, А.И. Практикум по микробиологии: учеб.пособие для студ. высш. учеб. заведений / А.И. Нетрусов, М.А. Егорова, Л.М. Захарчук и др.;под. ред. А.И. Нетрусова. - М.: Издательский центр «Академия», 2005. - 608 с.

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