Affiliation
a Amur State University, Blagoveshchensk, Russia
b Kemerovo State University, Kemerovo, Russia
c RED Solution provider, Hemel Hempstad, United Kingdom
Copyright ©Praskova et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0. (
http://creativecommons.org/licenses/by/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for any purpose, even commercially, provided the original work is properly cited and states its license.
Received 20 January, 2021 |
Accepted in revised form 19 February, 2021 |
Published 25 March, 2021
Abstract
Introduction. Population aging is a medical and social problem that receives special attention from the governments of developed and developing countries. The research objective was to assess the content of biologically active substances in fruits and leaves of Vitis amurensis Rupr. harvested in the Amur Region. The authors analyzed the phenolic profile, anti-radical potential, and the possibility of their complex processing for further use in functional foods.
Study objects and methods. The author reviewed ten years of domestic and foreign publications, standards, and legislative documents. The research featured leaves and fruits of Vitis amurensis Rupr., collected in various areas of the Amur Region. The composition of biologically active substances was analyzed using potentiometric, titrimetric, colorimetric, and photocolorimetric methods, as well as the method of X-ray fluorescence analysis.
Results and discussion. The sugar content in fruits of Vitis amurensis Rupr. was 11.97%, in leaves – 1.14%. In the fruits, the maximum calcium content was 62.57 ± 0.01 mg/100 g. Potassium content was the highest in the leaves (0.105 ± 0.004 mg/100 g). Caftaric acid had the largest content in leaves and fruits: 4.97 ± 0.01 and 125.69 ± 0.32 mg/kg, respectively. The highest content of resveratrol was found in fruits (148.16 ± 1.40 mg/kg), while in leaves it was only 9.87 ± 0.61 mg/kg. Likewise, fruits demonstrated the maximum content of flavonols: quercetin – 136.21 ± 5.60 mg/kg, kaempferol – 1.19 ± 0.01 mg/kg.
Conclusion. Vitis amurensis Rupr. is a promising source of bioactive compounds. Due to its comprehensive phytochemical assessment, it can find wider application in nutritive sciences, cosmetic industry, and food combinatorics. Fruits and leaves of Vitis amurensis Rupr. proved to possess a high antioxidant activity due to polyphenols, resveratrol, B vitamins, and vitamin C.
Keywords
Vitis amurensis Rupr.,
phenolic compounds,
vitamins,
mineral composition,
preventive nutrition
REFERENCES
- Federalʹnaya sluzhba gosudarstvennoy statistiki [Federal State Statistics Service] [Internet]. [cited 2020 Dec 15]. Available from: https://gks.ru.
- Kimble R, Keane KM, Lodge JK, Howatson G. Dietary intake of anthocyanins and risk of cardiovascular disease: A systematic review and meta-analysis of prospective cohort studies. Critical Reviews in Food Science and Nutrition. 2019;59(18):3032–3043. https://doi.org/10.1080/10408398.2018.1509835.
- Dalgaard F, Bondonno NP, Murray K, Bondonno CP, Lewis JR, Croft KD, et al. Associations between habitual flavonoid intake and hospital admissions for atherosclerotic cardiovascular disease: a prospective cohort study. The Lancet Planetary Health. 2019;3(11):e450–e459. https://doi.org/10.1016/S2542-5196(19)30212-8.
- Yadav K, Pandav CS. National iodine deficiency disorders control programme: Current status & future strategy. Indian Journal of Medical Research. 2018;148(5):503–510. https://doi.org/10.4103/ijmr.IJMR_1717_18.
- Biban BG, Lichiardopol C. Iodine deficiency, still a global problem? Current Health Sciences Journal. 2017;43(2):103–111. https://doi.org/10.12865/CHSJ.43.02.01.
- Ruban NYu, Reznichenko IYu. Preferences of people of advanced and gerontic age in diet formation. Food Processing: Techniques and Technology. 2020;50(1):176–184. (In Russ.). https://doi.org/10.21603/2074-9414-2020-1-176-184.
- Puzin SN, Pogozheva AV, Potapov VN. Optimizing nutrition of older people as a mean of preventing premature aging. Problems of Nutrition. 2018;87(4):69–77. (In Russ.). https://doi.org/10.24411/0042-8833-2018-10044.
- Anisimov VN, Bordovskiy GA, Finagentov AV, Shabrov AV. State support to elderly citizens: which gerontology needs modern Russia? (Part 1). Advances in Gerontology. 2020;33(4):616–624. (In Russ.). https://doi.org/10.34922/AE.2020.33.4.001.
- Anisimov VN, Bordovskiy GA, Finagentov AV, Shabrov AV. State support to elderly citizens: which geriatric needs modern Russia? (Part 2). Advances in Gerontology. 2020;33(4):625–645. (In Russ.). https://doi.org/10.34922/AE.2020.33.4.002.
- Momot TV, Kushnerova NF. Justification of the choice of raw sources from far east flora for receiving the pharmaceutical preparations. Izvestia of Samara Scientific Center of the Russian Academy of Sciences. 2016;18;(2):146–149. (In Russ.).
- Stepakova NN, Reznichenko IYu, Kiseleva TF, Shkrabtak NV, Frolova NA, Praskova YuA. Vegetable raw materials of the Far Eastern region as a source of biologically active substances. Food Industry. 2020;(3):16–21. (In Russ). https://doi.org/10.24411/0235-2486-2020-10025.
- Sebastian RS, Wilkinson Enns C, Goldman JD, Moshfegh AJ. Dietary flavonoid intake is inversely associated with cardiovascular disease risk as assessed by body mass index and waist circumference among adults in the United States. Nutrients. 2017;9(8). https://doi.org/10.3390/nu9080827.
- Kiselev KV, Aleynova OA, Tyunin AP. Expression of the R2R3 MYB transcription factors in Vitis amurensis Rupr. plants and cell cultures with different resveratrol content. Genetika. 2017;53(4):460–467. (In Russ.). https://doi.org/10.7868/S0016675817040099.
- Aleynova OA, Dubrovina AS, Khristenko VS, Kiselev KV. Kulʹtura kletok Vitis amurensis Rupr. kak alʹternativnyy istochnik protivoopukholevogo rezveratrola [Cell culture of Vitis amurensis Rupr. as an alternative source of antitumor resveratrol]. Biotekhnologiya kak instrument sokhraneniya bioraznoobraziya rastitelʹnogo mira (fiziologo-biokhimicheskie, ehmbriologicheskie, geneticheskie i pravovye aspekty): materialy VII Mezhdunarodnoy nauchno-prakticheskoy konferentsii [Biotechnology as a tool for preserving plant biodiversity (physiological, biochemical, embryological, genetic, and legal aspects): Proceedings of the VII International scientific and practical conference]; 2016; Simferopol. Simferopol: Arial; 2016. p. 170–171. (In Russ.).
- Reznichenko IYu, Frolova NA. The influence of climatic conditions on the biological value of berry raw materials of the amur region. Storage and Processing of Farm Products. 2018;(4):92–100. (In Russ.).
- El Khawand T, Courtois A, Valls J, Richard T, Krisa S. A review of dietary stilbenes: sources and bioavailability. Phytochemistry Reviews. 2018;17(5):1007–1029. https://doi.org/10.1007/s11101-018-9578-9.
- Chen Q, Diao L, Song H, Zhu X. Vitis amurensis Rupr: A review of chemistry and pharmacology. Phytomedicine. 2018;49:111–122. https://doi.org/10.1016/j.phymed.2017.08.013.
- Pressman P, Clemens RA, Hayes AW. Bioavailability of micronutrients obtained from supplements and food: A survey and case study of the polyphenols. Toxicology Research and Application. 2017;1. https://doi.org/10.1177/2397847317696366.
- Herman F, Westfall S, Brathwaite J, Pasinetti GM. Suppression of presymptomatic oxidative stress and inflammation in neurodegeneration by grape-derived polyphenols. Frontiers in Pharmacology. 2018;9. https://doi.org/10.3389/fphar.2018.00867.
- Vlasov VV, Muliukina NA, Zeleneanscaia NN, Ghereţchii RV. Primenenie BIO- i DNK-tekhnologiy v NNTS “IViV im. V.E. Tairova” [Application of BIO and DNA technologies in the NSC “IViV im. V.E. Tairova”]. Biotehnologii avansate – realizări și perspective; 2019; Chisinau. Chisinau, 2019. p. 20. (In Russ.).
- Kedrina-Okutan O, Novello V, Hoffmann T, Hadersdorfer J, Schneider A, Schwab W, et al. Polyphenolic diversity in Vitis sp. leaves. Scientia Horticulturae. 2019;256. https://doi.org/10.1016/j.scienta.2019.108569.
- Rasines-Perea Z, Teissedre PL. Grape polyphenols’ effects in human cardiovascular diseases and diabetes. Molecules. 2017;22(1). https://doi.org/10.3390/molecules22010068.
- Santos AC, Rodrigues D, Sequeira JAD, Pereira I, Simões A, Costa D, et al. Nanotechnological breakthroughs in the development of topical phytocompounds-based formulations. International Journal of Pharmaceutics. 2019;572. https://doi.org/10.1016/j.ijpharm.2019.118787.
- Frolova NA, Reznichenko IYu. Investigation of the chemical composition of fruit and berry raw materials of the Far Eastern Region as a perspective source of nutrients and bioactive compounds. Problems of Nutrition. 2019;88(2):83–90. (In Russ.). https://doi.org/10.24411/0042-8833-2019-10021.
- He F, Chen W-K, Yu K-J, Ji X-N, Duan C-Q, Reeves MJ, et al. Molecular and biochemical characterization of the UDPglucose: Anthocyanin 5-O-glucosyltransferase from Vitis amurensis. Phytochemistry. 2015;117:363–372. https://doi.org/10.1016/j.phytochem.2015.06.023.
- Mrduljaš N, Krešić G, Bilušić T. Polyphenols: Food sources and health benefits. In: Hueda MC, editor. Functional food. Improve health through adequate food. IntechOpen; 2017. pp. 23–41. https://doi.org/10.5772/intechopen.68862.
- Zheng F, Han M, He Y, Zhang Y, Liu S, Yue H, et al. Biotransformation of anthocyanins from Vitis amurensis Rupr of “Beibinghong” extract by human intestinal microbiota. Xenobiotica. 2019;49(9):1025–1032. https://doi.org/10.1080/00498254.2018.1532132.
- Frolova NA. Confectionery products of reduced energy value for aged people food. Bulletin of the South Ural State University. Series: Food and Biotechnology. 2020;8(1):74–80. (In Russ.).
- Tyunin AP, Nityagovsky NN, Grigorchuk VP, Kiselev KV. Stilbene content and expression of stilbene synthase genes in cell cultures of Vitis amurensis treated with cinnamic and caffeic acids. Biotechnology and Applied Biochemistry. 2018;65(2):150–155. https://doi.org/10.1002/bab.1564.
- Tufarelli V, Casalino E, D’Alessandro AG, Laudadio V. Dietary phenolic compounds: Biochemistry, metabolism and significance in animal and human health. Current Drug Metabolism. 2017;18(10):905–913. https://doi.org/10.2174/1389200218666170925124004.
- Zahedipour P, Asghari M, Abdollahi B, Alizadeh M, Danesh YR. A comparative study on quality attributes and physiological responses of organic and conventionally grown table grapes during cold storage. Scientia Horticulturae. 2019;247:86–95. https://doi.org/10.1016/j.scienta.2018.11.077.
- Morgado S, Morgado M, Plácido AI, Roque F, Duarte AP. Arbutus unedo L.: From traditional medicine to potential uses in modern pharmacotherapy. Journal of Ethnopharmacology. 2018;225:90–102. https://doi.org/10.1016/j.jep.2018.07.004.
- Tomaz I, Štambuk P, Andabaka Ž, Preiner D, Stupic D, Maletic E, et al. The polyphenolic profile of grapes. In: Thomas S, editor. Grapes: Polyphenolic composition, antioxidant characteristics and health benefits. Nova Science Pub Inc; 2017. pp. 1–70.
- Leal C, Gouvinhas I, Santos RA, Rosa E, Silva AM, Saavedra MJ, et al. Potential application of grape (Vitis vinifera L.) stem extracts in the cosmetic and pharmaceutical industries: Valorization of a by-product. Industrial Crops and Products. 2020;154. https://doi.org/10.1016/j.indcrop.2020.112675.
- Martins V, Billet K, Garcia A, Lanoue A, Gerós H. Exogenous calcium deflects grape berry metabolism towards the production of more stilbenoids and less anthocyanins. Food Chemistry. 2020;313. https://doi.org/10.1016/j.foodchem.2019.126123.
- Gouot JC, Smith JP, Holzapfel BP, Walker AR, Barril C. Grape berry flavonoids: A review of their biochemical responses to high and extreme high temperatures. Journal of Experimental Botany. 2019;70(2):397–423. https://doi.org/10.1093/jxb/ery392.
- Cory H, Passarelli S, Szeto J, Tamez M, Mattei J. The role of polyphenols in human health and food systems: A minireview. Frontiers in Nutrition. 2018;5. https://doi.org/10.3389/fnut.2018.00087.
- Xiang J, Apea-Bah FB, Ndolo VU, Katundu MC, Beta T. Profile of phenolic compounds and antioxidant activity of finger millet varieties. Food Chemistry. 2019;275:361–368. https://doi.org/10.1016/j.foodchem.2018.09.120.
- De Oliveira Caland RB, Cadavid COM, Carmona L, Peña L, De Paula Oliveira R. Pasteurized orange juice rich in carotenoids protects Caenorhabditis elegans against oxidative stress and β-amyloid toxicity through direct and indirect mechanisms. Oxidative Medicine and Cellular Longevity. 2019;2019. https://doi.org/10.1155/2019/5046280.
How to quote?
Praskova JuA, Kiseleva TF, Reznichenko IYu, Frolova NA, Shkrabtak NV, Lawrence Yu. Biologically Active
Substances of Vitis amurensis Rupr.: Preventing Premature Aging. Food Processing: Techniques and Technology. 2021;51(1):
159–169. (In Russ.). https://doi.org/10.21603/2074-9414-2021-1-159-169.