Affiliation
a N. I. Pirogov Russian National Research Medical University
b Moscow State University ofFood Production
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Abstract
A limited placebo-controlled study was conducted to assess the effect of per os intake of four dairy starter cultures composed of probiotic lactic acid bacteria and bifidobacterium on the intestinal microbiota of healthy volunteers. The four starter cultures included: (a) Lactobacillus casei B-1144, (b) L. acidophilus 593.40.3, (c) L. plantarum B-1615, and (d) a mixture of Bifidobacterium dentium 49B, B. animalis 52B and B. longum 53B. The comparison of intestinal microbiota in groups of volunteers receiving probiotic cultures against that in the group of volunteers receiving placebo revealed a number of quantitative changes. These included higher levels of obligate anaerobic bacteria belonging to the genus of Bacteroides , Atopobium, and Clostridium coccoides groups. In addition some of the starter cultures induced higher levels of lactobacilli and non-pathogenic E. coli . No statistically significant changes were observed in the group of volunteers receiving placebo.
Keywords
Probiotics,
bifidobacteria,
lactobacilli,
intestinal microbiota,
dairy products
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