Affiliation
a Associate Professor of the Department of Marketing and Business Communications, Kemerovo State University, docent, candidate of technical sciences
b Deputy Director for Science and Innovations, Research and manufacturing association "ArtLifeˮ, candidate of medical sciences
c Director of the Institute of Nutrition, Federal Research Center of Nutrition and Biotechnology, professor, doctor of medical sciences
d Head of the Research and Education Center "Processing of Agricultural Raw Materials and Food Technologiesˮ, Head of the Department of Food Industry and Functional Nutrition, Kemerovo State Agricultural Institute, professor, doctor of biological sciences
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Abstract
Clinical tests were carried out in the representative group of patients with focal left-sided pneumonia (5 men and 7 women aged 18–41). Special-use product was included in in-patient department patients’ diet: 2 tablets in the first intake, then 1 tablet 4 times a day. Course of treatment was 21 days. Biologically active dietary supplement was prescribed together with general therapeutic treatment according to generally accepted standards of care. Control group included 15 patients randomized depending on sex and age who took only medicine. The author measured body temperature, studied the results of general blood tests, determined the level of C-reactive protein and seromucoids, performed R-graphy of lungs, electrocardiogram before and after treatment, analyzed clinical symptoms (cough, type of expectoration, shortness of breath). Composition of the special-use product was scientifically justified taking pharmacological characteristics of its ingredients and their active agents into account. Introduction of the biologically active dietary supplement in addition to the prescribed therapeutic treatment gave positive effect in relation to the inflammatory process: the patients could easier clear their throats from expectoration, coughed less frequently, and had less intense shortness of breath. It was evident that symptoms of disease recrudescence decreased. It appeared in the decreased intensity and length of fever. In case of acute respiratory viral infection the biologically active dietary supplement had antipyretic activity due to the anti-exudative effect of its ingredients. The author determined the anti-inflammatory effect and reduction of acute intoxication symptoms taking the results of general blood analysis into account. Patients who took special-use product had lower values of an inflammatory process marker – seromucoids. Tissues restored easily. The tested product has anti-inflammatory, antipyretic and analgesic properties. It can be used in complex treatment of acute inflammatory diseases and recrudescence of chronic inflammatory processes.
Keywords
Full-scale tests,
biologically active dietary supplement,
vegetable components
REFERENCES
- Poznyakovskiy V.M., Chugunova O.V., Tomova M.Yu. Pishchevyye ingrediyenty i biologicheski aktivnyye dobavki [Food ingredients and biologically active dietary supplements]. Moscow: INFRA-M Publ., 2017. 143 p.
- Vekovcev A.A., Podzorova G.A., Kazʼmina A.Ju., Poznyakovskiy V.M. Naturnyye issledovaniya effektivnosti biologicheski aktivnoy dobavki s napravlennymi funktsional’nymi svoystvami [Field studies of the effectiveness of dietary supplements with aimed functional properties]. Tekhnika i tekhnologiya pishchevykh proizvodstv [Food Processing: Techniques and Technology]. 2015, no. 2(37), pp. 67–74.
- Bokeriya L.A. Zdorov’ye Rossii. Atlas [Russian health. Atlas]. Moscow: A.N. Bakulev National Medical Research Center of Cardiovascular Surgery Publ., 2012. 408 p.
- Pokrovskiy V.I., Romanenko G.A., Knyazev V.A., et al. Politika zdorovogo pitaniya. Federal’nyy i regional’nyy urovni [Healthy nutrition policy. Federal and regional levels]. Novosibirsk : Sibirskoye universitetskoye izdatel’stvo Publ., 2002. 344 p.
- Gerasimenko N.F., Poznyakovskiy V.M., Chelnokova [i.e. Chelnakova] N.G. Zdorovoye pitaniye i ego rol’ v obespechenii kachestva zhizni [Healthy eating and its role in ensuring the quality of life]. Tekhnologii pishchevoy i pererabatyvayushchey promyshlennosti APK – produkty zdorovogo pitaniya [Technologies of Food and Processing Industry of AIC – Healthy Food], 2016, no. 4(12), pp. 52–57.
- Gerasimenko N.F., Poznyakovsky V.M., Chelnakova [i.e. Chelnakova] N.G. Metodologicheskie aspekty polnotsennogo, bezopasnogo pitaniya: znachenie v sokhranenii zdorov’’ya i rabotosposobnosti [Methodological aspects of adequate safe nutrition: meaning for health promotion and maintenance of working capacity]. Chelovek. Sport. Meditsina [Human. Sport. Medicine], 2017, vol. 17, no. 1, pp. 79–86. https://doi.org/10.14529/hsm170108.
- Khadjieva Z.D. Opredeleniye glitsirrizinovoy kisloty v syr’ye i preparatakh solodki metodom VEZHKH [Glycyrrhizic acid definition in raw material and in glycyrrhiza preparations through the highly effective liquid 188 chromatography method]. Vestnik novykh meditsinskikh tekhnologiy [Journal of New Medical Technologies], 2006, vol. 13, no. 3, pp. 188–190.
- Shelemet’yeva O.V., Slepchenko G.B., Avstriyevskikh A.N. Kontrol’ soderzhaniya vodorastvorimykh vitaminov v biologicheski aktivnykh dobavkakh, pishchevykh produktakh i premiksakh metodom vysokoeffektivnoy zhidkostnoy khromatografii [Control over water-soluble vitamin content in biologically active dietary supplements, food and premixtures using high-performance liquid chromatography]. Zavodskaya laboratoriya. Diagnostika materialov [Industrial Laboratory. Diagnostics of Materials], 2008, vol. 74, no. 5, pp. 6–9.
- Ponomaryova E.I., Lukina S.I., Magomedov M.G., Roslyakova K.E. Production technology of functional bakery products. European Journal of Natural History, 2015, no. 6, p. 59.
- Shamtsyan M. Potential to develop functional food products from mushroom bioactive compounds. Journal of Hygienic Engineering and Design, 2016, vol. 15, pp. 51–59.
- Gorlov I.F., Slozhenkina M.I., Zlobina E.Y., et al. New functional products with chickpeas: reception, functional properties. American Journal of Food Technology, 2016, vol. 11, iss. 6, pp. 273–281. https://doi.org/10.3923/ajft.2016.273.281.
- Patrascu L., Vasilean I., Banu I., Aprodu I. Functional properties of pulse flours and their opportunities in spreadable food products. Quality Assurance and Safety of Crops and Foods, 2017, vol. 9, no. 1, pp. 67–78. https://doi.org/10.3920/QAS2015.0770.
- Avstriyevskikh A.N., Vekovtsev A.A., Poznyakovskiy V.M. Produkty zdorovogo pitaniya: novyye tekhnologii, obespecheniye kachestva, effektivnost’ primeneniya [Healthy foods: new technologies, quality assurance, efficiency of administration]. Novosibirsk: Sibirskoye universitetskoye izdatel’stvo Publ., 2005. 432 p.
- TR TS 027/2012. O bezopasnosti otdel’nykh vidov spetsializirovannoy pishchevoy produktsii v tom chisle dieticheskogo lechebnogo i dieticheskogo profilakticheskogo pitaniya [Technical Regulation of the Customs Union 027/2012. On safety of certain types of specialized food products including therapeutic and preventive dietary food]. Available at: file:///C:/Users/%D0%A6%D0%A1%D0%9D%D0%98/Downloads/o-bezopasnosti-otdelinyh-vidov-spetsializirovannoi-pi.pdf. (accessed 21 February 2018).
