Affiliation
a Kemerovo State University
b Research and manufacturing association «АrtLife»
c Kemerovo Institute of Food Science and Technology(University)
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Abstract
Evidence-based formulation of dietary supplement, the functional orientation of which is caused by synergistic effect of the prescribed components factors for the metabolism in chronic cerebrovascular insufficiency is developed. Efficacy and functional orientation of the specialized product was confirmed by the results of clinical trials, through its inclusion in the diet of patients with I-II stage dyscirculatory encephalopathy of vascular origin (DE). Patients received 1 capsule of the “OleoprenNeuro” dietary supplements 2 times a day for a month (DE-ON group). A similar group of 30 patients did not take supplements, and served as a control group. The clinical symptom course in patients with I-II DE group and the control group after treatment was studied. Materials that characterize the life quality in patients with I-II stage DE control group and DE-ON were obtained. It is shown that the complex treatment with the deitary supplement “OleoprenNeuro” of patients with vascular genesis dyscirculatory encephalopathy of I-II stage has a positive effect on the clinical disease: improvement in mood and state of health, and consequently the life quality is noted; favourable evolution in the treatment of cephalic and vestibule-ataksic syndromes is defined, as well as improving the cognitive functions of patients; it is well tolerated and does not cause any side effects. The results of the research show a positive role of polyprenols and vitamin E composing the dietary supplements, in the treatment of dyscirculatory encephalopathy of vascular origin of I-II stage. The clinical evidence allows the recommendation of the specialized product as an additional nutrition factor in the presence of these diseases.
Keywords
Dietary supplements,
a prescription formulation,
clinical trials,
diet therapy efficacy,
functional orientation
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